METHODS The concentrations of luteolin and apigenin in plasma were determined by HPLC method after a single oral dose of 200 mg · kg-1 of intact CME and hydrolysate of CME was administered to rabbits. 方法健康家兔单剂量(200mg·k-1)灌胃CME及其酸水解产物,以RP-HPLC测定给药后不同时间点木犀草素和芹菜素血浆药物浓度。